Is Effexor Killing me?
The past two weeks have been very hard for me. I’m not at all myself. I wonder though, am I too much of me. That I am myself now and I can’t deal with myself. I’m not sure.
I want to start out by saying, I’m not joining the Effexor nay-sayers. The medication is a good medication. With all medications, there are serious potential complications. If I could get pure Effexor, I wouldn’t be having the problems I’m having. Effexor is a good anti-depressant. The drug itself is not the problem in my case.

What’s the problem? I ran out of Effexor at the start of the month. The pharmacy was out. When I learned I would not be able to get it for five days, I was panicked. In the past, I missed my dose for a couple days. Those times, I didn’t realized I hadn’t taken it and I became aggressive, depressed and angry. Not a good place at all. The thought of going five days without that medication was horrifying to me. I can’t express the dread I had. The fear I had. I felt like I should be caged and hidden away so that I don’t do anything harmful. I’m not dangerous, I don’t think anything could cause me to harm someone. The only exception would be to protect family. When family has been threatened, I’ve been surprised how I responded. My bravery surprised me after the event was over. I am only afraid of what I might say. I am unhappy with some of my thoughts!
This drug is not addictive but there is something known as withdrawal syndrome associated with stopping it. Let me explain how these drug work, from a layman’s point of view. So it may not be 100% accurate but I’m not a doctor and you probably are not either.
Methamphetamine causes the users brain to be flooded with a “feel good” chemical. I don’t remember the name. It does this by causing an increase in production of the chemical. Its bad because it puts too much strain on the brain, burning it out. Effexor increases the amount of same chemical in the brain. The difference though is that Effexor doesn’t cause your brain to produce more but rather it keeps it floating around for your brain to use longer. This results in more of the chemical in the brain. Effexor also increased the level of serotonin. A second “feel good” chemical. Again but causing it to be in the brain longer. This is how most anti-depressant work.
When these level drops fast, your brain doesn’t like it. You can become suicidal. Just the thought of going through it is enough to cause some increase in suicidal indention. Some become homicidal. I can understand that feeling too. It causes me serious problems with anger. Intense anger. Unjustified anger. exaggerated anger beyond what the situation calls for. I internalize this though. If I strike out, it will be verbally.
There have been times in my life where I have been wronged, as we all have. The problem I have is I tend to obsess on it. I would have to admit. obsessed beyond what is normal. When that happens, it starts to build an anger in me. And the anger makes the obsession worse and the obsession makes the anger worse. So there’s my flaw and it feeds on itself. I’ve worked very hard on this but to make it completely go away? Even calling on my faith, my success has been limited at times. Returning to that state scares me. I do not want to be in that place. Being aware of this is the first step in improving. Becoming aware of this is no small feat in itself. Most people can’t do that. So please, before you start trying to take the splinter out of my eye, are you sure your vision is all that clear? Its really hard to see into our subconscious. We can’t do that alone.
Anyway back to the medication. You might ask why I don’t just get back on it. I surely thought I would. For the last year, I’ve been itching badly. My legs and arms are all clawed up. I break out in blisters. Its a lot like Poison Ivy.
A few days after I ran out of Effexor, the itching stopped! I counted back to when I started getting Effexor within the Philippines. That was May of last year. Before that, I had still been using the medication I got from the USA.
Cutting Medications In The Philippines
Why would it matter where I got the medication? There is a too common practice in the Philippines that I call cutting. Some where along the line, someone removes part of the ingredients within the capsule and worse, they put a filler in it. I believe that something was put in my medication that I have been reacting too.
The immediate “withdrawal” I experienced from this outage was nothing like it should have been. I had and am still having the “brain zaps” that so many people that stop taking it refer too. They are almost gone now. The anxiety levels I should have experienced were far less severe than I expected. After a couple of days, I was like wow, that was fairly easy compared to the past.
When I put the reduced itching together with the less than expected problems with stopping the medication, that leaves me with the feeling that my conclusion are not unfounded.
The itching has been bad. Since December of last year, I’ve been taking a lot of Benadryl. Probably four tablets a day. That kept the itching down but didn’t stop it. If I went outside, away from my air conditioner, the itching became unbearable. I stopped going outside. I’ve hardly been out of my bedroom for the last four months. I couldn’t enjoy anything.
I had gone from walking 1.5 miles a day. Now I almost never leave my bedroom! This has not been good for my health either. I need to walk, if I don’t, I’m going to die. I’ll die sooner rather than later. I have so many health issues. I’ll see if I can name them. They include, lupus, an enlarged heart, liver problems (I rarely drink), diabetes, morbid obesity and hypertension. I need to walk and I was so proud that I had been doing so well. Walking also helped me deal with the warmer environment here.
Now, I’ve been smoking heavy. That scares me and if i don’t die before I get the chance to quit, I will. I started the night I started getting the brain zaps. That when I found out I was out of Effexor. Right now, I gotta hold my mental health together. I’ve had some close calls in dealing with people in the last week. I finally isolated myself from everyone. Especially my online friends and association. I’m a wild man right now. Its all I can do to hold my unjustified anger in at times or perceived wrongs. And oh geesh, when I was wronged. That was bad.
The mental stress is making me physically ill. I felt very bad much of the last two weeks.
I’m not at all sure I should publish this article. I know I’m not alone in what I’m going through. I’m not sure that people experiencing it will comment. There is such a stigma associated with this kind of thing. Its worse than being gay in the early 70′s! I didn’t chose this. I don’t want it to be this way. Yet, still, when I’ve been open about it in the past, I’ve been ridiculed. Having someone hatefully say, “he must be off his meds” is hard for me to take. I didn’t do anything to deserve this kind of fate. If you do it here you wont be posting here again. If you’re that evil that you get a thrill out of it. Go for it. Not a lot bothers me. I’ve been through enough that it is hard to get to me. I’m also just smarter than most people and know they don’t understand. LOL I’m only half jesting. I do think I have some insights into human nature that most others don’t have. I got it from lots of therapy. I got it from looking within and not liking what I saw and then coming to terms with and working to change it.
This article is getting long, so I will wrap it up. Many of my friends have asked what is going on. Right now when people ask me how I’m doing, don’t give the expected, I’m doing very well. I’m not doing that for sympathy or even empathy. I’m doing it because I’m afraid of loosing friends. I’ve been here before. I’d like the outcome to be different this time. So, I’ve opened myself up. I hope you don’t cause me to regret it. To me this is a medical crises. I keep shaking my head. I don’t know what else to say and I don’t know how this is going to end up. I’ve got a long history of surviving, like most humans. I suspect I will do so again.
On the upside, wow do I feel alive. There is a renewed passion and excitement about some things that had dulled for me a bit. I’d like to be able to just stay off anything. I’ve tried to get Zoloft. I have not been able to find it either. You have to keep in mind, I live in what is little more than a jungle village. Its a good life but for the last two weeks, it has been hell. I do think what I’m doing is working, I am getting slowly better.
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Tagged with: Mental Health • Philippines
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I think posting this article was a mistake.
No one as been cruel. Just the opposite but it has also revealed that the level of misunderstanding is vast. Much wider than I realized and way to great for me to try to close the gap.
I will probably remove it.
Hi Rus, I’m sorry to hear of your difficulties in obtaining these meds. And I did not know that some Phil pharmacies can “cut” the efficacy of the meds by substitution. Perhaps explains why people who were on antibiotics took a bit longer to get better as opposed to antibiotics that come from here?? Anyway, this article is still informative, so perhaps leave if for awhile?
I supposed PI do not stock the newer drugs that are freely available in the west. Zoloft is considered “old” drug, so I hardly see it prescribed in the hospital I worked for here. In fact, I haven’t given Zoloft for probably a good 5 years if not more. I hope you’ll find some reliable source of Venlafaxine soon. It is not pleasant dealing with withdrawals at all.
Capsules are the problem regarding cutting. Jessie tells me not a problem with the major pharmacy chain. Don’t think my doctor believes it at all. He wrote another prescription for it. That is discouraging to me.
I don’t think the major Pharmacies would have anything to do with that. I don’t know for a fact that is what is going on with me. Kind of looks that way. I read some articles about it happening and a small family owned Pharmacy was charged with the practice. Here is an article on the subject but it involved medications out of China. http://www.gmanews.tv/story/47795/P500-M-fake-drugs-seized-in-Tondo-warehouse
I don’t think I’ll get it here at all.
I hope its withdrawal I’m dealing with. If so, it will pass. If its just me without the medication and ihs is the way its going to stay, something will have to change. I can’t enjoy life this way.
A good article Rusty i enjoyed it and i am wishing , hoping and praying for you to get thru these trying times :) :) ….and have a good day … a friend Phil :)
Thanks Phil. I THINK it is beginning to ease now.
Now I have to stop smoking again.
Today has been hard though, I lost most of the vision in my right eye for about five hours. It is mostly back. I admit, I’m feeling worn out, beat up and ready to just give up. Not in me though, don’t think I have a give up gene though sometimes I wish I did.
I’ll probably right about the episode tomorrow. I’ve been pretty scared today.
a friend of mine told that whenever you have a problem,, atleast be a solution to those who has a greater problem than you… try to go to villages where poor people lives,,,when you made sometning that make them happy and smile,, you will go home felling better,,,thats one way to ease the pain…..
When this was at its worst, it was best if I was around no one. :) I get angry over nothing. I fight it but it wins out. Its better now.
There is always someone in worse shape than me.
I prefer to help people to help them. If I do it in order to feel better then I gave for all the wrong reasons. I also don’t talk about helping others. I try to keep it a secret. When my right hand gives its best to not even let my left hand know. :)
yep..its better to help without knowing that it was you…Let our good lord gives credit to what you did,,,its more fulfilling…God is a;ways good to those who did good deeds…let our lord gives the reward,,maybe not today…but he is preparing the best for yoou
hi rusty hope you feel better. my wife had the same problem it took her 4 months to get through it now she feels great and has more energy.
Energy you say…. :) I THINK I know what you mean.
I survived many years without it but maybe I just didn’t know I need it. LOL
I’m doing much better. Still some brain zaps, still a bit of a short fuse and smoking way too much. I’m ready to try to quit that again. I did what I had to, to get through it. I was very fearful. It wasn’t as bad as I expected.
My itching is still better but b no means gone.
I got withdrawl symptoms from effexor also, I ended up in the hospital because of it. I’ll let you in on a secret, 80% of the people that take anti depressents show no improvement. I suggest getting your thyroid tested and a saliva cortisol test done. Using testosterone cream might help also. I hope you start feeling better soon. Good Luck !
Dan, that number comes from Scientology and totally inaccurate. They have so much trash out on the web about it and other antidepressants that its hard to find anything factual and useful any more.
They also blame crazy things crazy people do on the drug.
the medications are very effective.
Effexor is no longer causing me issues. Thanks I hope I get to feeling better soon too. :)
Rusty,
Your health problems are all due to the fact that your nervous system, specifically your neurotransmitter function, is shot. You know this. You are in what I like to think of “neurotransmitter hell”. I’ve dealt with this for ten years, and can mostly control it without prescription medication or self medication with drugs (alcohol, tobacco, etc.). I’m prone to everything from severe migraines to severe depression and anxiety.
First I developed a lifestyle program that increased neurotransmitter function. If you email me I will give you some tips. However, I want you to also look into 5 htp and tyrosine to help you with your issues. 5 htp causes the body to make more serotonin, not just recirculate it like SSRIs do, and tyrosine causes the body to make more dopamine and neuroepinephrine. Raising one depletes the other, and therefore both serotonin and dopamine must be supplemented for in conjunction.
I want you to look at the information on this website: http://www.neuroassist.com/
There is no cost, you just have to read, Specifically their protocols, which you can try. Everything that you need is relatively inexpensive, over the counter, and can be bought online. Make no mistake, that the effects of 5 htp and tyrosine are powerful. Just because they are over the counter, don’t underestimate the potency. As a matter of fact, I take much less than the above website recommends to great effect. You don’t want to overdue it, but go slowly to gauge your personal progress.
If any of this interests you, I want you to email me before you try any of it, as I have some insights after taking these supplements for a while that will greatly aid in them being both more effective. Also, I would want to make sure that you got the necessary info off of the above website to insure that you are safely and effectively taking what you would be taking.
Go read up on reviews for 5 htp as it relates to depression and anxiety. Most are extremely positive, and most say that it works far better than SSRI’s without near the side effects or withdrawal symptoms. Check it out.
Good luck.
Hey Chris, Thanks for your long comment! I thought you were a spammer but I checked and re-checked and you seem real. LOL These medical issue articles are targeted by spammers. They like to post their comments on multiple sites as they think it improves links back to their sites but it doesn’t even do that.
My first impression was you may be right. I’m surprised that site didn’t mention lupus in the menu on the left. Maybe I’m not fully understanding though, I should go look up up neurotransmitters again. Been a while since I dug in that deep.
Synaptic nerves are connective tissue. Lupus is a connective tissue disease. I think you could be correct that most of my problems could be traced back to this. If this connection is misfiring then some data sent to the brain is being lost or distorted. That would seem to include everything going on in my body.
However, i have grown very weary of supplements. Very skeptical. I’ve read so much, tried a few things. Even claiming they are not drugs is misleading. Of course they are. Just because the FDC doesn’t step in and call them drugs does not make them not drugs. I’ll try to spend some time on that site but I have been doing this for too long and I have no faith in any of these things. DHEA helped me some. I should probably be taking it. One thing I can assure you I wont do, is pay the extremely high prices of most suppliments. What use to seem like not such a high price, now seems insane to me. I didn’t see anything for sale there but I’m going to guess its there. No?
Sorry I just been through this too many t imes.
The website seems to be saying I can’t help myself with this approach:
I live in the Philippines.
hi rusty,i was on effexor for quite a few years and i ran into the same problems,if i ran out temporarily say 24 hours i too experienced terrible withdrawals after about two years of trying i finally was able to get off it completely,i haven’t taken this drug in over a year and actually i don’t even think it helped me anyway,btw i cut down slowly by halving then quartering the capsules.ken
Its not the drug to get on and off of, I’m certain of that. I can see a change in me when I’m not on it. In some ways the change is good and in some ways, not so good. I need to take something. I guess I just ain’t right in the head. LOL Grrrrrr. Sucks to admit that. :) I need to find something else that comes in a tablet.
lots of us aren’t quite normal,in fact i’d say its normal to be un-normal,actually i’ve went through most of the anti-depressants,tranquilizers and sleeping pills and although i’m still not “normal” i’m doing pretty good,it helps just knowing that a place like bantayan island exists gives me a lot of comfort
Bantayan is a peaceful place. :)
Hey Rusty,
I’ve been reading your blogs and I appreciate your info from Bantayan a lot.
So when I read that you are having problems with your health and you want to quit smoking I have a tip for you. Contact these guys in Carcar City and buy some snuff and use that instead. Of course, it’s the next best thing compared to quitting tobacco totally but at least it will save your lungs.
That’s how I quit smoking several years ago.
Take car and please write more from Bantayan soon.
Hey Peter thanks!
I am not a fan of snuff. I’d rather have burning lungs. :)
I’m doing pretty well with quitting, of course, t here have been some setback but the worst part of it is that I want to smoke. I don’t want to quit and that is making it much harder.
I had to remove your link, can’t promote tobacco products. It could get me banned from my advertisers. Sorry Thanks for the attempted help…
I need to go back to Bantayan!
He he, the choice between burning lungs or a burn under your upper lip seems easy but then again I was more or less born in to using snuff as many other Swedish males.
Its good that you removed the link. I do not want to advertise tobacco either. It’s not good for your health in any form but is true that snuff can help you quit smoking.
I know what you mean when you say the problem is that you want to smoke. Its just one of thoose things that makes life a little more pleasant and it is strange that thoose little habits are allways bad for your health. Cigars, Whiskey and beautiful women……can all be hazardous, but life w/o them is so boring.
Anyway, I really enjoy reading your blogs and maybe we will run in to each other on Bantayan some day ? I’m easy to spot because I look a lot like you and I will be on or near the floating bar. Might even be under the floating bar if its one of thoose days :-)
Take care Rusty and please keep you and your blogs alive.
Have you read what snuff does? Mouth and throat cancer rates are staggering. I’d rather smoke myself. Snuff and chewing tobacco gross me out and a lot of the people around me but its also less intrusive to others. The habit still seems to bother even more people, with the need to spit. I’d go for the burning lungs over the burning gums. LOL
I might get some cigars that helps if I don’t inhale the stupid things. LOL
Its getting easier. I just need to stop stealing the occasional one from a friend or stay away from those that smoke till I get further removed from it.
Ecstasy also released serotonin in the brain but not just a little at a time, ALL of it at once. Causing a wild and great time…that is till you wake up in the morning feeling like complete garbage.
Yeah, X does that but it causes you to actually release it. Effexor just slows down the bodies use of it. Keep it in the blood longer. X will deplete your brain of it and then you’re screwed.